Antibacterial Activity Test of Moringa Leaf Ethanol Extract Ointment of Moringa oleifera Lamk. on Staphylococcus aureus Bacteria

Miladiarsi; Nasrawati Basir; Nurlindasari; Wahdaniar; Ade Irma

doi:10.56741/hesmed.v2i01.222

Authors

Miladiarsi
miladiarsibio@gmail.com
Universitas Megarezky, Indonesia
Nasrawati Basir Universitas Megarezky, Indonesia
Nurlindasari Universitas Megarezky, Indonesia
Wahdaniar Universitas Megarezky, Indonesia
Ade Irma Universitas Megarezky, Indonesia

DOI:

https://doi.org/10.56741/hesmed.v2i01.222

Keywords:

Antibacterial, Moringa leaves, Ointment preparations, Staphylococcus aureus

Abstract

Staphylococcus aureus is gram-positive bacteria and can cause infections and disorders of the skin. This study aims to determine the physical stability of ointment preparations containing ethanol extract from Moringa leaves based on variations in concentration and antibacterial activity against Staphylococcus aureus. This research is a laboratory experiment with the stages of making an ointment from the ethanol extract of Moringa leaves and testing its antibacterial activity against Staphylococcus aureus. Data analysis using One-Way ANOVA. The results of the research on moringa leaf ethanol extract ointment preparations were physically and chemically stable through organoleptic testing, homogeneity, dispersion, viscosity, and pH by including a cycling test. Antibacterial activity test showed that moringa leaf ointment had antibacterial activity against Staphylococcus aureus with the diameter of the inhibition zone each extract concentration of 15% (16.1mm), 20% extract concentration (17.3mm), 25% extract concentration (18.1mm) in inhibiting bacteria staphylococcus aureus. Ethanol extract ointment preparations with each concentration have a strong category of inhibition against the Staphylococcus aureus bacteria.

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Author Biographies

Miladiarsi, Universitas Megarezky, Indonesia

Miladiarsi is an education scientist, lecturer, and head of the Biomedical Science Study Program, Health Tecnology Faculty, Megarezky University, Makassar, Indonesia. Her bachelor is from Universitas Hasanuddin, and mater from Institut Pertanian Bogor. (email: miladiarsi.bio09@gmail.com).

Nasrawati Basir, Universitas Megarezky, Indonesia

Nasrawati Basir is an education scientist, lecturer of Pharmacy Study Program, Faculty of Pharmacy, Megarezky Universitiy Makassar, Indonesia. Her bachelor and master degree were graduated from Universitas Hasanuddin, Indonesia. Her research interset is in the post-incidence therapy. (email: nasrawatibasir@gmail.com).

Nurlindasari, Universitas Megarezky, Indonesia

Nurlindasari is a student of the Pharmacy Study Program, Faculty of Pharmacy, Megarezky University Makassar, Jalan Antang Raya No.4, Makassar 90234, Indonesia. (email: nurlinda.sari@gmail.com).

Wahdaniar, Universitas Megarezky, Indonesia

Wahdaniar is an education scientist, lecturer of the Biomedical Science Study Program, Health Technology Faculty, Megarezky University, Makassar, Jalan Antang Raya No.4, Makassar 90234, Indonesia. Her degree is from Universitas Islam Negeri Alauddin Makassar for bachelor degree and Universitas Diponegoro for master degree. (email: niarwahdaniar03@gmail.com).

Ade Irma, Universitas Megarezky, Indonesia

Ade Irma is an education scientist, lecturer of the Biomedical Science Study Program, Health Technology Faculty, Megarezky University, Makassar, Jalan Antang Raya No.4, Makassar 90234, Indonesia. Her degree is from Universitas Hasanuddin for bachelor degree and Institut Pertanian Bogor for master degree. (email: adeirmabio93@gamail.com ).

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