Association between Maternal Body Mass Index and Preeclampsia Incidence
Evidence from Bantul Hospital, Indonesia
DOI:
https://doi.org/10.56741/hesmed.v5i01.2184
Keywords:
Body Mass Index, Maternal Childbirth, Obesity, Preeclampsia, Risk Factors
Abstract
Preeclampsia remains one of the leading causes of maternal mortality worldwide and is closely associated with several risk factors, particularly obesity. According to the World Health Organization, preeclampsia affects approximately 2–8% of pregnancies globally and contributes substantially to maternal deaths. In Indonesia, preeclampsia accounts for around 25% of maternal mortality cases. In Bantul Regency, the number of preeclampsia cases increased significantly from 161 cases in 2023 to 320 cases in 2024. Obesity is recognized as an important risk factor that can increase the likelihood of preeclampsia, while Body Mass Index (BMI) is widely used to assess maternal nutritional status. However, evidence regarding the relationship between BMI and preeclampsia at PKU Muhammadiyah Bantul Hospital is still limited. This study aimed to determine the association between BMI and the incidence of preeclampsia among mothers giving birth at PKU Muhammadiyah Bantul Hospital during 2024–2025. This study employed an observational analytical design with a case-control approach. A total of 322 respondents were selected through purposive sampling using complete medical record data. Data analysis was conducted using the Chi-Square test and Odds Ratio (OR). The results showed a significant relationship between BMI and preeclampsia incidence (p = 0.001). Obese mothers were found to have a substantially higher risk of developing preeclampsia compared with non-obese mothers (OR = 48.450; 95% CI: 22.578–103.967). These findings emphasize the importance of routine BMI screening during antenatal care for early detection and prevention of preeclampsia.
Downloads
References
M. F. Melesse, G. L. Aynalem, M. B. Badi, and B. Y. Aynalem, “Maternal outcomes of severe preeclampsia and eclampsia and associated factors among women admitted at referral hospitals of Amhara regional state, institutional-based cross-sectional study, North-West Ethiopia,” Front. Glob. Women’s Heal., vol. 6, no. March, pp. 1–8, 2025, doi: 10.3389/fgwh.2025.1555778. DOI: https://doi.org/10.3389/fgwh.2025.1555778
WHO, “Pre-eclampsia,” WHO, 2025, [Online]. Available: https://www.who.int/news-room/fact-sheets/detail/pre-eclampsia. (Accessed: Nov. 10, 2025).
K. J. Chang, K. M. Seow, and K. H. Chen, “Preeclampsia: Recent Advances in Predicting, Preventing, and Managing the Maternal and Fetal Life-Threatening Condition,” Int. J. Environ. Res. Public Health, vol. 20, no. 4, 2023, doi: 10.3390/ijerph20042994. DOI: https://doi.org/10.3390/ijerph20042994
B. P. Statistik, “Angka Kematian Ibu,” Angka Kematian Ibu/AKI (Maternal Mortality Rate/MMR) Has. long form SP 2020 Menurut provinsi,2020, 2020, [Online]. Available: https://www.bps.go.id/id/statistics-table/1/MjIxOSMx/angka-kematian-ibu-aki-maternal-mortality-rate-mmr-hasil-long-form-sp2020-menurut-provinsi-2020.html. (Accessed: Nov. 11, 2026). [Eng. Trans.: Maternal Mortality Rate].
Kemenkes RI, Profil Kesehatan Indonesia 2023. 2024. [Online]. Available: https://kemkes.go.id/id/profil-kesehatan-indonesia-2023. (Accessed: Nov. 10, 2025). [Eng. Trans.: Indonesia Health Profile 2023].
Dinas Kesehatan Provinsi DIY, “Profil Kesehatan DIY 2023,” Profil dan Buku Data Kesehat. 2023, 2024, [Online]. Available: https://dinkes.jogjaprov.go.id/page/8b5b455c-466b-49ea-a944-c82416baa273. (Accessed: Nov. 11, 2025). [Eng. Trans.: DIY Health Profile 2023].
Dinkes Bantul., “Laporan Kerja Dinas Kesehatan Kabupaten Bantul,” Dinas Kesehat. Bantul, pp. 53–54, 2023, [Online]. Available: https://dinkes.bantulkab.go.id/storage/dinkes/document/394/LKJ-DINKES-TAHUN-2023.pdf. (Accessed: Nov. 14, 2025). [Eng Trans : Performance Report of the Bantul District Health Office].
Kesga DIY, Laporan Kesehatan Ibu. 2025. [Online]. Available: https://kesgadiy.web.id/laporan-kesehatan-ibu. (Accessed: Nov. 09, 2025). [Eng. Trans.: Maternal Health Report].
D. A. Lestari, E. Juniarty, and A. Fitriyah, “Hubungan Paritas Dan Obesitas Dengan Kejadian Preeklampsia Pada Ibu Hamil Di Rumah Sakit Umum Daerah Kota Prabumulih,” J. Ilmu Kebidanan dan Kesehat. (Journal Midwifery Sci. Heal., vol. 15, no. 2, pp. 88–94, 2024, doi: 10.52299/jks.v15i2.284. [Eng. Trans.: The Correlation Between Parity and Obesity with the Incidence of Preeclampsia in Pregnant Women at Prabumulih City Regional General Hospital]. DOI: https://doi.org/10.52299/jks.v15i2.284
Kemenkes RI, Buku Saku Merencanakan Kehamilan Sehat. 2021. [Online]. Available: https://repository.kemkes.go.id/book/874. (Accessed: Nov. 05, 2025). [Eng. Trans.: Pocket Book for Planning a Healthy Pregnancy].
D. E. Jeong et al., “The association between maternal pre-pregnancy body mass index and pregnancy outcomes of preeclampsia,” Taiwan. J. Obstet. Gynecol., vol. 61, no. 3, pp. 441–446, 2022, doi: 10.1016/j.tjog.2022.03.008. DOI: https://doi.org/10.1016/j.tjog.2022.03.008
L. Zhang et al., “Relationship between prepregnancy BMI and gestational weight gain(GWG) with preeclampsia: a study based on restricted cubic spline,” BMC Pregnancy Childbirth, vol. 25, no. 1, 2025, doi: 10.1186/s12884-025-07449-8. DOI: https://doi.org/10.1186/s12884-025-07449-8
K. Nadia, I. Isnaniah, F. J. Laili, and N. R. Prihatanti, “Hubungan Indeks Massa Tubuh Dengan Kejadian Pre Eklamsia Di Puskesmas Pekapuran Raya Kota Banjarmasin Tahun 2024,” J. Penelit. Multidisiplin Bangsa, vol. 1, no. 8, pp. 1270–1279, 2025, doi: https://doi.org/10.59837/jpnmb.v1i8.234. [Eng. Trans.: The Relationship Between Body Mass Index and the Incidence of Pre-eclampsia at Pekapuran Raya Public Health Center, Banjarmasin City in 2024]. DOI: https://doi.org/10.59837/jpnmb.v1i8.234
M. A. Aziz, A. Wibowo, N. L. Almira, and T. Sutjighassani, “Relationship of Age, Body Mass Index, Gravida, and Parity in Pregnant Women with the Incidence of Preeclampsia,” Indones. J. Obstet. Gynecol. Sci., vol. 5, no. 2, pp. 208–216, 2022, doi: 10.24198/obgynia/v5n2.389. DOI: https://doi.org/10.24198/obgynia/v5n2.389
A. Susanti, “Gambaran Faktor-Faktor Resiko Kejadian Preeklamsia Pada Ibu Hamil Di RS PKU Muhammadiyah Bantul Yogyakarta,” Univ. Aisyiyah Yogyakarta, pp. 1–19, 2020, [Online]. Available: https://digilib.unisayogya.ac.id/5167/. [Eng. Trans.: Overview of Risk Factors for Preeclampsia in Pregnant Women at RS PKU Muhammadiyah Bantul Yogyakarta].
Kemenkes RI, “BAB 5 Kesehatan Keluarga 2023,” Profil Kesehatan Indonesia 2023. 2023. [Online]. Available: https://layanandata.kemkes.go.id/katalog-data/profil-kesehatan/ketersediaan-data/profil-kesehatan-2023. (Accessed: Nov. 25, 2026). [Eng. Trans.: Chapter 5 Family Health 2023].
S. Rahayu, N. S. Murni, Akhmad, and Yusnilasari, “Analisis Determinan Kejadian Preeklampsia Pada Ibu,” J. Kesehat. Tambusai, vol. 5, no. 3, pp. 6991–7004, 2024, [Online]. Available: https://journal.universitaspahlawan.ac.id/index.php/jkt/article/view/29789. [Eng. Trans.: Determinant Analysis of Preeclampsia Incidence in Mothers]. [Eng. Trans.: Determinant Analysis of Preeclampsia Incidence in Mothers].
M. Reddy Eleti, M. Agrawal, D. Dewani, and N. Goyal, “Serum LDH Levels in Normotensive and Preeclamptic-Eclamptic Pregnant Women and Its Correlation With Fetomaternal Outcome,” Cureus, vol. 15, no. 4, 2023, doi: 10.7759/cureus.37220. DOI: https://doi.org/10.7759/cureus.37220
A. Regita and Y. N. Khayati, “Riwayat Preeklampsia, Usia dan Paritas Ibu Meningkatkan Resiko Preeklampsia, Studi Case Control di RSUD Gondosuwarno Ungaran,” J. Holistics Heal. Sci., vol. 6, no. 2, pp. 230–240, 2024, doi: 10.35473/jhhs.v6i2.483. [Eng. Trans.: History of Preeclampsia, Maternal Age, and Parity Increase the Risk of Preeclampsia: A Case-Control Study at RSUD Gondosuwarno Ungaran]. DOI: https://doi.org/10.35473/jhhs.v6i2.483
R. R. Dzikrullah, Ismawati, and Norrmantany, “Hubungan Antara Paritas, Interval Paritas, dan Usia Ibu dengan Kejadian Preeklampsia di Kabupaten Karawang Tahun 2021,” Bandung Conf. Ser. Med. Sci., vol. 3, no. 1, pp. 1–7, 2023, doi: 10.29313/bcsms.v3i1.7142. [Eng. Trans.: The Relationship Between Parity, Parity Interval, and Maternal Age with the Incidence of Preeclampsia in Karawang Regency in 2021]. DOI: https://doi.org/10.29313/bcsms.v3i1.7142
E. Susanti, M. Ruspita, and S. Isharyanti, “Parity And Body Mass Index As Factors In Preeclampsia Incidence,” J. Ris. Kesehat., vol. 13, no. 2, pp. 145–152, 2024, doi: 10.31983/jrk.v13i2.11651. DOI: https://doi.org/10.31983/jrk.v13i2.11651
WHO, “Obesity and overweight,” WHO, 2025, [Online]. Available: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight. (Accessed: Nov. 10, 2025).
R. Rahmayanti and F. Zahra, “Hubungan Obesitas dengan Kejadian Preeklampsia,” J. khatulistiwa Nurs. J., vol. 7, no. 1, pp. 97–104, 2025, doi: 10.53399/knj.v7i1. [Eng. Trans.: The Relationship Between Obesity and the Incidence of Preeclampsia]. DOI: https://doi.org/10.53399/knj.v7i1.321
F. Mukhtar, “A Systematic Review of the Management of Maternal Obesity in Pregnancy: Antenatal Management, Outcomes, and Long-Term Implications on Maternal Health,” Cureus, vol. 17, no. 7, 2025, doi: 10.7759/cureus.87258. DOI: https://doi.org/10.7759/cureus.87258
V. J. Vera-Ponce, J. A. Loayza-Castro, J. Ballena-Caicedo, L. A. M. Valladolid-Sandoval, F. E. Zuzunaga-Montoya, and C. I. Gutierrez De Carrillo, “Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis,” Front. Reprod. Heal., vol. 7, no. November, pp. 1–18, 2025, doi: 10.3389/frph.2025.1706009. DOI: https://doi.org/10.3389/frph.2025.1706009
J. Torres et al., “A Narrative Review on the Pathophysiology of Preeclampsia,” Int. J. Mol. Sci., vol. 25, no. 14, pp. 1–24, 2024, doi: 10.3390/ijms25147569. DOI: https://doi.org/10.3390/ijms25147569
D. A. R. Fadiah, N. Mona, F. S. Rachmat, S. D. Anna, and W. G. Sri, “Prevalensi Preeklamsia YangTerjadi pada Tahun 2020 - 202221 di RSIA Sitti Khadijah 1 Muhammadiyah Makassar,” Innov. J. Soc. Sci. Res., vol. 4, no. 2, pp. 6483–6493, 2024, [Online]. Available: https://j-innovative.org/index.php/Innovative/article/view/9970. [Eng. Trans.: The Prevalence of Preeclampsia Occurring in 2020 - 2022 at RSIA Sitti Khadijah 1 Muhammadiyah Makassar].
N. Veri, L. Lajuna, C. Mutiah, Halimatussakdiah, and Dewita, “Preeeklamsia: patofisiologi, diagnosis, skrining, pencegahan dan penatalaksanaan,” Fem. J. Ilm. Kebidanan, vol. 4, no. 1, pp. 283–296, 2024, doi: 10.30867/femina.v4i1.588. [Eng. Trans.: Preeclampsia: Pathophysiology, Diagnosis, Screening, Prevention, and Management]. DOI: https://doi.org/10.30867/femina.v4i1.588
Y. T. Chiang, K. M. Seow, and K. H. Chen, “The Pathophysiological, Genetic, and Hormonal Changes in Preeclampsia: A Systematic Review of the Molecular Mechanisms,” Int. J. Mol. Sci., vol. 25, no. 8, 2024, doi: 10.3390/ijms25084532. DOI: https://doi.org/10.3390/ijms25084532
A. G. Dickerson, C. A. Joseph, and K. Kashfi, “Current Approaches and Innovations in Managing Preeclampsia: Highlighting Maternal Health Disparities,” J. Clin. Med., vol. 14, no. 4, pp. 1–23, 2025, doi: 10.3390/jcm14041190. DOI: https://doi.org/10.3390/jcm14041190
P. Gaur, P. M.L., J. Schulkin, and A. C. Jelin, “Associations of Preconception BMI and Hypertension with Preeclampsia,” J. Women’s Heal., 2023, doi: 10.1089/jwh.2023.0083. DOI: https://doi.org/10.1089/jwh.2023.0083
F. N. Aini, F. Zuhriyatun, and W. Hapsari, “Indeks Massa Tubuh (Imt) Dengan Kejadian Preeklampsia Pada Ibu Hamil,” J. Sains Kebidanan, vol. 5, no. 1, pp. 24–29, 2023, doi: 10.31983/jsk.v5i1.9696. [Eng. Trans.: Body Mass Index (BMI) and the Incidence of Preeclampsia in Pregnant Women]. DOI: https://doi.org/10.31983/jsk.v5i1.9696
I Gede Wara Nugraha and Rini Martina Siallagan, “Preeclampsia Risk in Bali, Indonesia: The Role of Maternal Body Mass Index (BMI) and Gestational Weight Gain (GWG),” Biosci. Med. J. Biomed. Transl. Res., vol. 9, no. 1, pp. 5923–5935, 2024, doi: 10.37275/bsm.v9i1.1164. DOI: https://doi.org/10.37275/bsm.v9i1.1164
I. A. Rifkiansyah, T. H. Yuliawati, Z. Faizah, and E. Ernawati, “Hubungan Obesitas pada Wanita Hamil yang Mengalami Preeklampsia,” J. Ners, vol. 10, no. 1, pp. 137–141, 2025, doi: 10.31004/jn.v10i1.51851. [Eng. Trans.: The Relationship of Obesity in Pregnant Women Experiencing Preeclampsia]. DOI: https://doi.org/10.31004/jn.v10i1.51851
J. Mao, H. Sun, Q. Shen, C. Zou, Y. Yang, and Q. Du, “Impact of pre-pregnancy body mass index on preeclampsia,” Front. Med., vol. 12, no. February, pp. 1–7, 2025, doi: 10.3389/fmed.2025.1529966. DOI: https://doi.org/10.3389/fmed.2025.1529966
B. Mészáros, Z. Kukor, and S. Valent, “Recent Advances in the Prevention and Screening of Preeclampsia,” J. Clin. Med., vol. 12, no. 18, 2023, doi: 10.3390/jcm12186020. DOI: https://doi.org/10.3390/jcm12186020
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Nur Baity Darojat, Dhesi Ari Astuti

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.










