Effect of Aloe Vera Gel in the Healing of Post Operating Incissions: Evidence Based Nursing
DOI:
https://doi.org/10.56741/hesmed.v1i02.127
Keywords:
aloe vera, incision wound, wound healing
Abstract
The incidence of injuries in the world throughout the year is increasing, both acute and chronic wounds. In Indonesia, the prevalence of incisional wounds is 8.2%. Wound healing can be assisted with herbal plants, one of which is aloe vera. The purpose of this evidence-based nursing study was to determine aloe vera's effectiveness in the healing process of incisional wounds. The method used is a literature review. Database searches were conducted through Pubmed, Science Direct, Science Open and Google Scholar. The inclusion criteria of the journal in this study were journals that examined incisions, cuts or surgical wounds given intervention using aloe vera in a quasi-experimental research design, case study, double-blind, controlled trial, journals published in 2016-2021 and used Indonesian or English. This study's results indicate an influence of aloe vera in the wound-healing process, especially in the proliferative phase. This literature study can be used as evidence-based nursing at the level of nursing health services, especially wound care management based on aloe vera.
Downloads
References
D. Mei et al., “Pegylated graphene oxide carried oh-cath30 to accelerate the healing of infected skin wounds,” Int. J. Nanomedicine, 2021, doi: 10.2147/IJN.S304702.
M. Petkovic, M. Vangmouritzen, B. Mojsoska, and H. Jenssen, “Immunomodulatory properties of host defence peptides in skin wound healing,” Biomolecules. 2021, doi: 10.3390/biom11070952.
X. Pang, N. Dong, and Z. Zheng, “Small leucine-rich proteoglycans in skin wound healing,” Frontiers in Pharmacology. 2020, doi: 10.3389/fphar.2019.01649.
Y. An et al., “Exosomes from adipose-derived stem cells and application to skin wound healing,” Cell Proliferation. 2021, doi: 10.1111/cpr.12993.
C. M. Han, B. Cheng, and P. Wu, “Clinical guideline on topical growth factors for skin wounds,” Burns and Trauma. 2020, doi: 10.1093/BURNST/TKAA035.
E. M. Tottoli, R. Dorati, I. Genta, E. Chiesa, S. Pisani, and B. Conti, “Skin wound healing process and new emerging technologies for skin wound care and regeneration,” Pharmaceutics. 2020, doi: 10.3390/pharmaceutics12080735.
I. Solaberrieta, A. Jiménez, I. Cacciotti, and M. C. Garrigós, “Encapsulation of bioactive compounds from aloe vera agrowastes in electrospun poly (ethylene oxide) nanofibers,” Polymers (Basel)., 2020, doi: 10.3390/polym12061323.
Elseena Jose, Shilpa Joseph, and Mariya Joy, “Aloe Vera and Its Biological Activities,” World J. Curr. Med. Pharm. Res., 2021, doi: 10.37022/wjcmpr.vi.167.
K. Bialik-Was, K. N. Raftopoulos, and K. Pielichowski, “Alginate Hydrogels with Aloe vera: The Effects of Reaction Temperature on Morphology and Thermal Properties,” Materials (Basel)., 2022, doi: 10.3390/ma15030748.
O. A. Ibrahim, A. A. Mohsin, M. H. Alhammashi, and J. S. Jafar, “The effect of commercial toothpaste containing Aloe Vera on dental plaque and gingivitis: A double-blind randomized clinical trial,” Int. Med. J., 2021, doi: 10.37506/ijfmt.v15i2.14862.
P. O. Samirana, N. W. Satriani, P. R. Harfa, S. P. P. Dewi, and C. I. S. Arisanti, “Formulasi Sediaan Krim Anti Luka Bakar dari Ekstrak Air Daging Daun Aloe Vera,” J. Kim., 2020, doi: 10.24843/jchem.2020.v14.i01.p07.
S. Govindarajan, S. N. Babu, M. A. Vijayalakshmi, P. Manohar, and A. Noor, “Aloe vera carbohydrates regulate glucose metabolism through improved glycogen synthesis and downregulation of hepatic gluconeogenesis in diabetic rats,” J. Ethnopharmacol., 2021, doi: 10.1016/j.jep.2021.114556.
Suhardono, Siswanto, J. Sugiharta, and A. T. Normawati, “The effect of aloe vera compress on the injection area of infusion to phlebitis incidences in local government hospital in Indonesia,” Journal of Critical Reviews. 2020, doi: 10.31838/jcr.07.04.105.
K. M. Katubi, A. Amari, H. N. Harharah, M. M. Eldirderi, M. A. Tahoon, and F. Ben Rebah, “Aloe vera as promising material for water treatment: A review,” Processes. 2021, doi: 10.3390/pr9050782.
L. Kaviya and J. Somasundaram, “Aloe vera as an herbal remedy in dentistry,” Int. J. Pharm. Res., 2020, doi: 10.31838/ijpr/2020.12.04.180.
M. K. Sharma, J. Chauhan, M. Kumar, C. K. Joshi, S. Sharma, and C. Lal, “Prospects of Aloe vera and its bioactive compounds in diabetes: Critical review,” Journal of Pure and Applied Microbiology. 2021, doi: 10.22207/JPAM.15.4.54.
N. I. Rasli, H. Basri, and Z. Harun, “Zinc oxide from aloe vera extract: two-level factorial screening of biosynthesis parameters,” Heliyon, 2020, doi: 10.1016/j.heliyon.2020.e03156.
A. Ikram et al., “Effect of adding Aloe vera jell on the quality and sensory properties of yogurt,” Food Sci. Nutr., 2021, doi: 10.1002/fsn3.2017.
R. Majumder, C. K. Das, and M. Mandal, “Lead bioactive compounds of Aloe vera as potential anticancer agent,” Pharmacological Research. 2019, doi: 10.1016/j.phrs.2019.104416.
S. A. Al-Maweri et al., “Efficacy of aloe vera mouthwash versus chlorhexidine on plaque and gingivitis: A systematic review,” International Journal of Dental Hygiene. 2020, doi: 10.1111/idh.12393.
A. Kumar, U. Shukla, T. Prabhakar, and D. Srivastava, “Hyperbaric oxygen therapy as an adjuvant to standard therapy in the treatment of diabetic foot ulcers,” J. Anaesthesiol. Clin. Pharmacol., 2020, doi: 10.4103/joacp.JOACP_94_19.
L. V. Tumay, S. Kılıcturgay, V. Savci, O. Saraydaroglu, and R. Anarat, “Effects of Aloe Vera on healing of colonic anastomoses: experimental rat study,” J. Coloproctology, 2019, doi: 10.1016/j.jcol.2018.10.010.
N. H. Mohd Nizam et al., “Physical, thermal, mechanical, antimicrobial and physicochemical properties of starch based film containing aloe vera: a review,” Journal of Materials Research and Technology. 2021, doi: 10.1016/j.jmrt.2021.08.138.
R. Kumar, A. K. Singh, A. Gupta, A. Bishayee, and A. K. Pandey, “Therapeutic potential of Aloe vera—A miracle gift of nature,” Phytomedicine, 2019, doi: 10.1016/j.phymed.2019.152996.
T. J. Boffeli and S. B. Hyllengren, “Unilobed Rotational Flap for Plantar Hallux Interphalangeal Joint Ulceration Complicated by Osteomyelitis,” J. Foot Ankle Surg., 2015, doi: 10.1053/j.jfas.2014.12.023.
A. Tornero-Martínez et al., “In vitro Fermentation of Polysaccharides from Aloe vera and the Evaluation of Antioxidant Activity and Production of Short Chain Fatty Acids,” Molecules, 2019, doi: 10.3390/molecules24193605.
S. Anand et al., “Multifunctional Biomimetic Nanofibrous Scaffold Loaded with Asiaticoside for Rapid Diabetic Wound Healing,” Pharmaceutics, 2022, doi: 10.3390/pharmaceutics14020273.
Yuliana, A. Johan, and N. Rochana, “Early Mobilization Increases Wound Healing On Post Laparatomy Patients,” Proc. Int. Nurs. Conf. Chronic Dis., 2019.
F. L. Game et al., “A systematic review of interventions to enhance the healing of chronic ulcers of the foot in diabetes,” Diabetes/Metabolism Research and Reviews. 2012, doi: 10.1002/dmrr.2246.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Sitti Syabariyah, Belinda Rizky Amalia, Nina Gartika
![Creative Commons License](http://i.creativecommons.org/l/by-sa/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.