Exploring the Streptococci Variants in Children’s Oral Cavity, Its Microbiome Diversity

Juniati Binti Lukman; Zaraswati Dwyana; Mochammad Hatta; Cyril B. Romero

doi:10.56741/hesmed.v2i02.264

Authors

Juniati Binti Lukman
juniatielukman@gmail.com
Universitas Megarezky
Zaraswati Dwyana Hasanuddin University https://orcid.org/0000-0001-5002-237X
Mochammad Hatta Hasanuddin University https://orcid.org/0000-0002-8456-4203
Cyril B. Romero University of Saint Anthony

DOI:

https://doi.org/10.56741/hesmed.v2i02.264

Keywords:

Lactic acid bacteria, Oral cavity, Oral microbiota, Streptococcus

Abstract

This study aimed to identify the variants of the Streptococcus genus in the oral cavity of healthy individuals. Streptococcus is one of the normal flora, which is part of the lactic acid bacteria (LAB) in the oral cavity. LAB has the ability to produce antimicrobial agents, regulate the host's immune response, and inhibit the growth of pathogenic bacteria. The presence of LAB in the oral cavity is crucial in maintaining oral health and preventing periodontal diseases. This study used observational cross-sectional design with 40 healthy elementary school children as subjects. Swabs were taken from their oral cavities and sent to the laboratory for PCR and sequencing tests. The results revealed that isolates 3S, 4S, 9S, 10S, 14S, and 15S were identified as Streptococcus dysgalactiae, while isolates 1S, 8S, and 9S were identified as Streptococcus mitis. Additionally, isolates 2S, 5S, 7S, 11S, 12S, and 13S were identified as Streptococcus salivarius, isolate 6S was identified as Streptococcus agalactiae, and isolate 17S was identified as Streptococcus oralis. These findings provide valuable information on the identification of oral microbiota, particularly Streptococcus genus variants, which can potentially serve as an alternative therapy for periodontal diseases.

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Author Biographies

Juniati Binti Lukman, Universitas Megarezky

is a lecturer in biomedical sciences at Megarezky Makassar University and a researcher at LPPS MIPA UNHAS. She has conducted various research in the field of biomedical sciences and has published several scientific papers. Her research interests include the development of new drugs and therapies for diseases, particularly those related to cancer.

Zaraswati Dwyana, Hasanuddin University

is a senior lecturer in the field of Microbiology in the Biology department of Mathematics and Natural Sciences Faculty, Universitas Hasanudin, Makassar, Indonesia. She is also actively involved as the chairman of quality assurance at Mathematics and Natural Sciences Faculty, Universitas Hasanudin. She has been contributing to research in the field of microbiology and has published several research papers in national and international journals.

Mochammad Hatta, Hasanuddin University

is a senior lecturer and researcher at the Faculty of Medicine at Hasanuddin University. He is an expert in clinical microbiology, molecular biology, epidemiology, and immunology of infectious diseases. He has published many scientific papers and conducted research in various fields related to infectious diseases. He is also active in scientific organizations and societies related to his field of expertise.

Cyril B. Romero, University of Saint Anthony

is an educator and lecturer. A graduate school Professor at the University of Saint Anthony, Iriga City, Philippines. She is a chairman/panel member/adviser of theses and dissertation writings. President of the CODHPE-Phil. (Council of Deans of Health Profession Education) and the Vice President of the ADPCN Reg. V (Association of Deans of the Phil. Colleges of Nursing), Past NOMELEC chair of ADPCN INC, National.

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