Potential of Harum Manis Mango (Mangifera Indica L.) Seed Extract for Nosocomial Infections

Wahdaniar; Imran Pashar; Miladiarsi; Ade Irma

doi:10.56741/jphs.v2i02.213

Authors

Wahdaniar
niarwahdaniar03@gmail.com
Universitas Megarezky
Imran Pashar Universitas Megarezky
Miladiarsi Universitas Megarezky
Ade Irma Universitas Megarezky

Keywords:

Harum Manis Mango, Health Science, Nosocomial Infections, Seed Extract

Abstract

Nosocomial infections occur in hospitals and attack patients who are in the recovery process and have low immunity. The emergence of nosocomial conditions in the hospital environment is caused by bacteria and moist objects or materials, especially in the operating room and even the treatment room for children and babies. One type of bacteria that causes the infection is Pseudomonas aeruginosa. P. aeruginosa has been recognized as an irreversible problem in hospitals due to resistance to 3 antibiotic classes. The content of sweet mango seeds has a high phytochemical content in the form of steroid compounds, terpenoids, flavonoids, alkaloids, phenolics, tannins and saponins. This study aimed to determine the potential of sweet mango seed extract against nosocomial infections. The research method is quantitative experimental, using ethanol extract of sweet fragrant mango seeds with well diffusion and dilution tests (MIC and MBC). The results of the antibacterial activity test measured the inhibition zone formed and tested MIC and MBC. MIC value of sweet fragrant mango seed extract showed at 1.56 mg/mL and 0.78, and at MBC value of 25 mg/mL and 50 mg/mL. The results of sweet fragrant mango seed extract have the potential to be developed as an antibacterial agent, especially against nosocomial infections.

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Author Biographies

Wahdaniar, Universitas Megarezky

is a lecturer at Biomedical Science Department. She is a secretary of Biomedical Science Study Program at Megarezky University. She is a journal reviewer for Journal of Health Sciences and Medical Development (email: niarwahdaniar03@unimerz.ac.id).

Imran Pashar, Universitas Megarezky

is a lecturer at Nursing Department of Universitas Megarezky, Sulawesi Selatan. His bachelor and professional degree are from Universitas Muhammadiyah Semarang. His master degree is from Universitas Diponegoro. (email: imranunimerz@gmail.com).

Miladiarsi, Universitas Megarezky

is a lecturer at Biomedical Science Department. She is Head of Biomedical Science Study Program at Megarezky University. Her research interest is in medical microbiology, and genetic epidemiology (email: miladiarsi.bio09@gmail.com).

Ade Irma, Universitas Megarezky

is a lecturer at Biomedical Science Department, Megarezky University. Her position is as Quality Control Taskforce in this university. She is active to promote education quality in health and medical sciences. (email: adeirmabio93@gmail.com).

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